HIV-1 Integrase–DNA Interactions Investigated by Molecular Modelling
نویسندگان
چکیده
منابع مشابه
HIV-1 integrase–DNA interactions investigated by molecular modelling
HIV-1 integrase is the viral enzyme responsible for the insertion of the viral DNA into the host cell chromosome. This process occurs through two distinct biochemical reactions: the 30-processing of the viral DNA and the transesterification reaction. Because experimental structural information on the reaction intermediate is not available, several molecular models have been developed. Unfortuna...
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ژورنال
عنوان ژورنال: Computational and Mathematical Methods in Medicine
سال: 2008
ISSN: 1748-670X,1748-6718
DOI: 10.1080/17486700802167918